what is the best way to get off cymbalta

Stopping Cymbalta could exist quite challenging, especially if the patients do not know how to practice it correctly. For weaning off Cymbalta successfully, it is vital to stick to the tapering schedule and never try to stop duloxetine abruptly because Duloxetine withdrawal tin can exist tough.

Although this antidepressant is not physically addictive, the withdrawal effects can be astringent and even life-threatening. Knowing how to reduce and manage symptoms of withdrawal from Cymbalta can help a person complete the treatment successfully and avoid relapsing.

Cymbalta Withdrawal: The Causes Behind

Frequently, patients will cull to finish duloxetine for a combination of reasons. For example, Cymbalta tin make patients gain weight in some cases, which tin happen in addition to the medication no longer existence constructive. When patients reach the point that they are because stopping duloxetine, they should speak to their md about their desire. Other adjustments may make the medication work for them. And should stopping exist the best class of activeness, they can help the patient quit taking the medication safely.

Doctor-and-patient-are-discussing-stopping Cymbalta.

Similar other antidepressant drugs, Duloxetine is rarely associated with dependence and withdrawal by the majority of patients. Notwithstanding, stopping information technology abruptly oftentimes results in some adverse effects, both physical and psychological. The symptoms are caused by Duloxetine withdrawal syndrome, typically referred to every bit discontinuation syndrome.

Similar most other antidepressants, duloxetine begins exerting therapeutic effects after information technology has built upwards in a person'due south system. This scheme puts the trunk through tremendous stress when the dose is suddenly changed, resulting in severe withdrawal symptoms.

A written report reports that Cymbalta withdrawal symptoms terminal for weeks and even months in some patients. It is also noted that equally many as 44% of patients taking Duloxetine experience some effects of discontinuation syndrome.

Cymbalta Withdrawal Symptoms

Withdrawal from Cymbalta tin can be both moderate and astringent. The symptoms frequently manifest as amplified side effects of taking Duloxetine. It is barely possible to compile a comprehensive Cymbalta withdrawal symptoms list since they differ from person to person; notwithstanding, medical professionals can distinguish the following most frequently reported effects.

Infographics with cymbalta withdrawal symptoms.

The Full List of Psychological Symptoms:

  • Depression
  • Anxiety
  • Agitation and irritability
  • Racing thoughts
  • Confusion
  • Nightmares
  • Hallucinations
  • Paranoia, hypomania, and other mental disorders
  • Persistent suicidal thoughts or self-harming behaviors

The Full List of Physical Symptoms:

  • Dizziness
  • Nausea
  • Headache
  • Tremors
  • Vomiting
  • Insomnia
  • Diarrhea
  • Excessive sweating
  • Irregular heartbeat
  • Seizures
  • Hypersensitivity

Another hazard of the symptoms mentioned above is their potential for causing other more severe health issues. For instance, if a person feels depressed subsequently quitting the medication, they might take a big dose to alleviate the disturbing feelings. Information technology might pb to duloxetine overdose and other wellness problems.

Encephalon Zaps

Encephalon zaps on Duloxetine are a common but not fully explained phenomenon. Patients depict the zaps every bit sudden electric buzzing in their caput. Sometimes the sensations extend to other parts of the body. Brain zaps caused past quitting the medication are often accompanied by disorientation and lightheadedness. While significantly disturbing to many, brain zaps are not known to present any health danger to the person.

How Long Does Cymbalta Stay in Your System?

Cymbalta half-life averages 12 hours. However, it tin happen sooner or take longer to occur, depending on the patient. It means that Duloxetine withdrawal can start approximately 12 hours later on taking the final dose of the drug. Knowing the duloxetine half-life is important, but it doesn't evidence the big picture.

The Verbal Length of Time of How Long Cymbalta Stays Detectable In the System Is Discussed Beneath:

  • Blood. When information technology comes to detection in the claret, duloxetine can exist seen on tests for up to five days after the last dose.
  • Urine. In the urine, it besides shows upwards for nigh 5 days.
  • Saliva. Saliva has the shortest detection menstruum of merely ii days after the last dose.
  • Pilus. On the other hand, hair has the longest detection time, which is possible upwards to ix months after last use.

Considering duloxetine can remain in the organisation for so long, it tin can take a while for the trunk to return to normal. For example, duloxetine sexual side effects may not go away for several weeks. And since 1 cannot take Cymbalta while significant, this can also determine when it is safe to conceive.

Withdrawal Timeline

People who experience the discontinuation syndrome ofttimes wonder how long Cymbalta withdrawal lasts. The process can be quite lengthy depending on the dose of the drug, how long a person has been receiving treatment, and other private characteristics. Overall, the procedure of detoxification and withdrawal can take upwards to several months.

The Showtime Symptoms

The first Duloxetine withdrawal symptoms appear after nigh 12 hours afterwards an individual ingested the concluding dose. At that fourth dimension, approximately half the consumed corporeality remains in the person'due south system, so the effects are likely to exist modest.

Later on 24 Hours

After 24 hours since the ingestion, the person might begin experiencing nausea, sweating, agitation, and other symptoms.

Woman experiencing nausea due to Cymbalta withdrawal.

The Subsequent Weeks

The physical side furnishings of duloxetine usually peak after 2-3 days and can persist for more than a week. The psychological symptoms of stopping duloxetine can concluding for months. Although they slowly fade with time, slap-up emotional disturbance tin trigger the return of low, feet, or whatever other mental health disorder that the antidepressant was intended to treat. The menses when patients get off duloxetine is also characterized by an increased run a risk of suicide.

At that place Is No Universal Timeline

The severity of withdrawal from Cymbalta and how long information technology takes to stop experiencing the symptoms depends on every patient'due south characteristics. Information technology is difficult to predict each person's response to the discontinuation of duloxetine. Therefore, medical supervision is strongly advised to help the patient quit duloxetine without damaging their health along the way.

Stopping Duloxetine Requires Medical Supervision

Many patients believe that they can get off the antidepressant on their own. Yet, stopping whatsoever antidepressant has the risk of health complications arising. Additionally, if a user switches medications without medical aid, there are risks of complications. It also refers to a situation when a patient stops using duloxetine in combination with other drugs such equally Cymbalta with Wellbutrin.

How To Stop Cymbalta

Stopping duloxetine can technically be done one of two ways: going cold turkey or tapering off the drug. Still, merely i method to cease taking Duloxetine is safety, and that is tapering. Going common cold turkey will trigger withdrawal, which is something the user will want to avert as it has the potential to exist deadly.

Quitting Cold Turkey

Knowing that stopping Cymbalta cold turkey is dangerous, information technology might seem odd that people would consider this method. Yet, it is not always by selection. When people lose their insurance or cannot beget the next month of pills, there is a possibility they will non have some other option.

However, not having other options does not mean stopping Cymbalta cold turkey volition be without consequences. On the mild end, the user will experience mild Cymbalta withdrawal from quitting common cold turkey. On the dangerous finish, stopping Cymbalta suddenly can trigger seizures, suicidal thoughts and could fifty-fifty put the patient into a coma.

Depressed woman after quitting Cymbalta cold turkey.

If someone is in a position where they feel they have no choice but to get cold turkey, they should contact their doctor to see if at that place is the assist they can offer them to cease using it safely.

Tapering Off

Tapering off Cymbalta, or weaning off the drug, is the safe way to stop use. However, information technology should exist done under medical supervision. There are right and incorrect means to taper, and following the proper taper schedule for the patient is critical to success. For some patients, it takes a few weeks to taper off, while others demand months.

A Typical Schedule for How to Taper off Cymbalta Is as Follows:

  • Starting dose – 90 mg
  • First Taper – 60 mg
  • Second Taper – 30 mg
  • Third Taper – 20 mg
  • 4th Taper – 10 mg

Withal, users should not merely follow this schedule. If they showtime at a higher dose or have been abusing the drug, a different plan is needed. Additionally, there could exist other complicating factors that necessitate altering the schedule. Always taper off with the assistance of a medico.

Are There FDA Guidelines On Stopping Cymbalta?

The FDA does not have whatsoever guidelines for how to come off Duloxetine safely. Information technology is unfortunate, as it means that there is not much research into weaning off Cymbalta successfully, and most doctors are working without the correct guidance. All the FDA suggests is that stopping be gradual and monitored by a doctor.

Withdrawal Handling

When information technology comes to Cymbalta withdrawal, assistance is available to enable people to overcome their dependence on the medication and ease the side effects. Fifty-fifty with tapering, there is no guarantee that withdrawal symptoms will be avoided entirely. Therefore, some patients volition need treatment for these symptoms. Sure antidepressant drugs like Prozac might be used one time to counter the psychological side furnishings of quitting duloxetine. Other medications might too be used to treat diarrhea, nausea, and insomnia.

The necessity to manage Cymbalta withdrawal extends well beyond the initial detox period. Various supportive and handling services are available to assist patients who endure from psychological dependence on duloxetine or get through a relapse.

Getting Help With Stopping Cymbalta

Withdrawal symptoms of Duloxetine can include astringent deterioration of a person's mental state, relapse of depression or feet, panic attacks, and an increased risk of suicide. The adverse effects might occur due to discontinuation syndrome or during detox for those who are addicted to the drug.

Whether someone wants to finish Cymbalta because they are abusing it or has another reason for quitting, they must do it carefully. Doctor supervision is critical, and for some, it will demand to be in a drug rehabilitation facility.

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Page Sources

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  2. Harvard Health Publishing, How to taper off your antidepressant, 2020. https://world wide web.health.harvard.edu/diseases-and-conditions/how-to-taper-off-your-antidepressant
  3. Us National Library of Medicine, MedlinePlus, Duloxetine. https://medlineplus.gov/druginfo/meds/a604030.html
  4. Stockmann, T., Odegbaro, D., Timimi, South., & Moncrieff, J. (2018). SSRI and SNRI withdrawal symptoms reported on an internet forum. International Journal of Chance & Safety in Medicine, 29(iii-4), 175-180. https://pubmed.ncbi.nlm.nih.gov/29758951/
  5. Fava, G. A., Benasi, Grand., Lucente, M., Offidani, E., Cosci, F., & Guidi, J. (2018). Withdrawal symptoms after serotonin-noradrenaline reuptake inhibitor discontinuation: systematic review. Psychotherapy and psychosomatics, 87(4), 195-203. https://pubmed.ncbi.nlm.nih.gov/30016772/
  6. Qadir, A., & Haider, N. (2006). Duloxetine withdrawal seizure. Psychiatry (Edgmont), iii(9), x. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963463/
  7. Henssler, J., Heinz, A., Brandt, L., & Bschor, T. (2019). Antidepressant withdrawal and rebound phenomena. Deutsches Ă„rzteblatt International, 116(20), 355. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637660/
  8. Perahia, D. 1000., Kajdasz, D. 1000., Desaiah, D., & Haddad, P. Yard. (2005). Symptoms following abrupt discontinuation of duloxetine treatment in patients with major depressive disorder. Journal of affective disorders, 89(one-3), 207-212. https://pubmed.ncbi.nlm.nih.gov/16266753/
  9. Wilson, E., & Lader, Chiliad. (2015). A review of the management of antidepressant discontinuation symptoms. Therapeutic advances in psychopharmacology, 5(half-dozen), 357-368. https://world wide web.ncbi.nlm.nih.gov/pmc/articles/PMC4722507/

Published on: May 30th, 2019

Updated on: July 20th, 2021

Sharon Levy, MD, MPH

After successful graduation from Boston University, MA, Sharon gained a Chief'southward degree in Public Health. Since and then, Sharon devoted herself entirely to the medical niche. Sharon Levy is likewise a certified habit recovery bus.

Medically Reviewed by

Michael Espelin APRN

8 years of nursing experience in wide variety of behavioral and addition settings that include adult inpatient and outpatient mental wellness services with substance use disorders, and geriatric long-term care and hospice care.  He has a detail involvement in psychopharmacology, nutritional psychiatry, and culling handling options involving detail vitamins, dietary supplements, and administering auricular acupuncture.

dentondiestlyped.blogspot.com

Source: https://addictionresource.com/drugs/cymbalta/stopping/

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